We introduce GenPhylo, a Python module that simulates nucleotide sequence
data along a phylogeny avoiding the restriction of continuous-time Markov
processes. GenPhylo uses directly a general Markov model and therefore
naturally incorporates heterogeneity across lineages. We solve the challenge of
generating transition matrices with a pre-given expected number of
substitutions (the branch length information) by providing an algorithm that
can be incorporated in other simulation software.
Este artículo explora los viajes en el tiempo y sus implicaciones.
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2504.15855v1